Upstream Manufacturing Associate

Upstream Processing Manufacturing Scientist

Upstream Processing Manufacturing Scientists in Piscataway, NJ. Responsible for executing Mammalian Cell Culture (CHO Cells). Cell culture batches from 50L to 1000L of volume.

Requirements

• Upstream Manufacturing experience

• Proficiency with single use manufacturing consumables (e.g., bags, tube sets, columns) and prior experience in scale-up manufacturing activities
• At least 12 years of experience in cell culture and bioreactor operations, including GMP and Aseptic Manufacturing experience
• Bioreactor experience
• Experience working in a GmP environment

Skills:

• Ability to work collaboratively within a team and an Upstream environment
• attention to detail
• Problem-solving skills

About the Role
Global Life Science Hub is recruiting on behalf of an innovative biopharmaceutical organization seeking a skilled Upstream Manufacturing Scientist. This is an excellent opportunity for a motivated professional to join a forward-thinking team, contributing to the production of mammalian-based biosimilars in a cGMP environment.

In this role, you’ll manage mammalian cell culture processes, working on bioreactor operations from 50L to 1000L volumes for engineering and clinical batches. You’ll bring technical expertise, teamwork, and an eye for detail to ensure production standards are met efficiently.

Key Responsibilities

• Execute upstream manufacturing processes with a collaborative team.
• Operate bioreactors at various scales, performing cell culture processes.
• Ensure timely execution of engineering and clinical batches.
• Develop and refine equipment specifications and...

Global Life Science Hub is partnered with an incredible biopharmaceutical company specializing in difficult-to-formulate biologics. Recently, the company has achieved 2 FDA approvals and is transitioning from R&D to a full-scale commercial organization looking to build a new state-of-the-art facility in New Jersey as they ramp up production efforts from 50L to 2000L in Q4.

We are searching for a passionate Upstream Manufacturing Associate with solid cell culture expertise to support the scale-up manufacturing efforts. The ideal candidate will have extensive experience working with CHO cells and perfusion-based bioreactor systems.

Responsibilities:

• Lead and execute upstream batches, including mammalian cell culture with a focus on CHO cell lines.
• Design, optimize, and troubleshoot cell culture processes in batch, fed-batch, and perfusion bioreactor systems.
• Maintain and scale up cell culture operations to support...

Global Life Science Hub is proud to partner with a specialised Biopharmaceutical company leading the charge of next-generation drug delivery technologies and oral//biosimilar drug development.

Having gathered 2 recent FDA approvals, they're in the process of gearing up for exponential growth. With brand new in-house Manufacturing capabilities set to triple production in 2025, this is an exciting time to join a rapidly expanding organization.

To support further expansion, the Upstream Manufacturing Associate/Scientist will be responsible for executing mammalian cell culture processes and producing proteins for a wide range of mammalian based biosimilars. The appointed candidate will require technical expertise in Cell Biology and Bioreactor Operations.

Responsibilities:

• Collaborate with a dynamic team of manufacturing associates and engineers to carry out upstream production batches.
• Conduct cell culture and manage bioreactor...